A light lunch will be served from 11.30 outside the venue on a first come – first served basis. If you would like to contact the speaker, please e-mail the host, Prof Suzanne Dickson, email@example.com.
About this seminar:
The speaker, Roger Adan, is a Professor of Molecular Pharmacology at the University Medical Center (UMC) Utrecht, the Netherlands. He also holds a Visiting Professorship at Sahlgrenska Academy.
Viral vectors revolutionize neuroscience as innovative tools to map neural circuits and record and manipulate activity of specific neurons within these circuits. In this seminar viral vectors are first use to map connections between leptin responsive neurons and dopamine neurons. Optogenetics-assisted circuit mapping is then used to functionally characterize these connections using electrophysiology. To determine which neurons mediate leptin’s effect on food reward, specific neurons are brought under control of a drug using chemogenetics. To further characterize these neurons, the activity of these neurons is recorded using fiber photometry and the transcriptome is analysed using RNAseq.