nov
2023
hörsal Arvid Carlsson, Academicum, Medicinaregatan 3
Nedbrytbara biomaterial, som magnesium (Mg), representerar lovande alternativ med lägre risk till nuvarande enheter.
Seminar for employees and students in areas such as dentistry and biomedicine. The event is free of charge and you do not need to register in advance. There will be no food in connection with the lecture.
Lecturer: Dr. Charles S. Sfeir, Associate Professor, Associate Dean for Research, Chair Periodontics, University of Pittsburgh, USA.
Degradable biomaterials, such as magnesium (Mg), represent promising and lower-risk alternatives to current devices that are fabricated primarily using permanent and inert metals, such as titanium and surgical stainless steel. Mg has been shown to 1) facilitate the process of bone repair by stimulating several bone specific pathways and local production of calcitonin gene-related peptide (CGRP) and 2) to immunomodulate macrophage response. Our laboratory has focused on studying the formation of bone around Mg-based implants which are placed below the periosteum. Our hypothesis is that Mg can stimulate osteogenesis of the periosteum and thus induce cell differentiation and local bone regeneration. In addition, we have used the ligature induced
periodontitis to study the immunomodulatory role of Mg. This presentation will provide data on the therapeutic effects of the local release of Mg and CGRP in the bone repair process as well as a
potential treatment of periodontal disease.
